pitanje

DA li beba uopšt ima CMV infekciu. Prvo pitanje je kako je ta dijagnoza utvrđena. Ako beba ima pozitivna CMV specifična antitela, onda su ona majčinska. Perinatalna infekcia se dokazuje na osnovu kliničke slik i dokaza CMV DNK PCR  tehnikom. Novorođenčad stiču CMV perinatalno, evo skračene verzije udžbeničkog teksta

Cytomegalovirus infection may be acquired prenatally or perinatally and is the most common congenital viral infection. Signs at birth, if present, are intrauterine growth restriction, prematurity, microcephaly, jaundice, petechiae, hepatosplenomegaly, periventricular calcifications, chorioretinitis, pneumonitis, hepatitis, and sensorineural hearing loss. If acquired later in infancy, signs may include pneumonia, hepatosplenomegaly, hepatitis, thrombocytopenia, sepsis-like syndrome, and atypical lymphocytosis. Diagnosis of neonatal infection is best made by viral detection via culture or polymerase chain reaction testing. Treatment is mainly supportive. Parenteral ganciclovir or oral valganciclovir may prevent hearing deterioration and improve developmental outcomes and is given to infants with symptomatic disease identified in the neonatal period.